Sequencings

Markers / Gene

ANKK1

One position in this gene is readable from a home DNA test.

Dopamine receptor density, the Taq1A variant

rs1800497 · chr11:113,270,828 · G/A · evidence: moderate

The reward system evolved to make you chase scarce things: sugar, fat, salt, status, novelty. This variant is associated with fewer dopamine D2 receptors in the striatum, and it has been studied in addiction and in the pull of highly palatable food. It is the mismatch argument in a single gene.

If you carryWhat it means
No copiesYou have the common version on both copies
One copyYou carry one copy
Two copiesYou carry two copies
Ancestry groupA (the effect version)
African38.5%
American31.1%
East Asian40.6%
European18.8%
South Asian31.5%

1000 Genomes Project phase 3, via Ensembl, retrieved 2026-09-23. These groupings are coarse and flatten a great deal of internal diversity, particularly within Africa. A variant being common somewhere tells you where a piece of your ancestry probably comes from, and nothing else.

Full detail on rs1800497

If you have taken a home DNA test, these positions are already in your file.

Read my file