Markers / Gene
CDKAL1
One position in this gene is readable from a home DNA test.
CDKAL1 and how much insulin you release
rs7756992 · chr6:20,679,709 · A/G · evidence: established
One of the first type 2 diabetes variants found, and one of the few that replicates in every population tested. It acts on how much insulin the pancreas puts out rather than on how well the body responds to it.
| If you carry | What it means |
|---|---|
| No copies | You have the lower-risk version on both copies |
| One copy | You carry one higher-risk copy |
| Two copies | You have the higher-risk version on both copies |
| Ancestry group | G (the effect version) | |
|---|---|---|
| African | 63.3% | |
| American | 30.0% | |
| East Asian | 47.2% | |
| European | 28.1% | |
| South Asian | 26.9% |
1000 Genomes Project phase 3, via Ensembl, retrieved 2026-09-23. These groupings are coarse and flatten a great deal of internal diversity, particularly within Africa. A variant being common somewhere tells you where a piece of your ancestry probably comes from, and nothing else.
Where this gene fits
If you have taken a home DNA test, these positions are already in your file.
Read my file