Sequencings

Markers / Gene

FADS1

One position in this gene is readable from a home DNA test.

Turning plant fats into the ones your brain runs on

rs174546 · chr11:61,569,830 · C/T · evidence: established

Your brain needs long-chain omega-3 and omega-6 fats. You either eat them ready-made, from fish and organ meat, or you build them from the short ones in plants. FADS1 does the building, and the efficient version swept through farming populations that ate mostly plants. Populations that kept eating fish never needed it, and Greenlandic Inuit carry a different version entirely, adapted the opposite way.

If you carryWhat it means
No copiesYou have the slower-converting version on both copies
One copyYou carry one efficient copy
Two copiesYou have the efficient version on both copies
Ancestry groupC (the effect version)
African97.8%
American41.4%
East Asian43.4%
European65.3%
South Asian86.3%

1000 Genomes Project phase 3, via Ensembl, retrieved 2026-09-23. These groupings are coarse and flatten a great deal of internal diversity, particularly within Africa. A variant being common somewhere tells you where a piece of your ancestry probably comes from, and nothing else.

Full detail on rs174546

If you have taken a home DNA test, these positions are already in your file.

Read my file