Markers / Gene
HCP5
One position in this gene is readable from a home DNA test.
Abacavir hypersensitivity marker
rs2395029 · chr6:31,431,780 · T/G · evidence: established
Abacavir, an HIV medicine, causes a dangerous hypersensitivity reaction in people carrying HLA-B*57:01. Testing before prescribing is mandatory, and it is one of the clearest successes in the whole field.
| If you carry | What it means |
|---|---|
| No copies | Tag not detected |
| One copy | Tag detected |
| Two copies | Tag detected, two copies |
| Ancestry group | G (the effect version) | |
|---|---|---|
| African | 0.5% | |
| American | 2.0% | |
| East Asian | 1.2% | |
| European | 4.4% | |
| South Asian | 9.3% |
1000 Genomes Project phase 3, via Ensembl, retrieved 2026-09-23. These groupings are coarse and flatten a great deal of internal diversity, particularly within Africa. A variant being common somewhere tells you where a piece of your ancestry probably comes from, and nothing else.
Where this gene fits
If you have taken a home DNA test, these positions are already in your file.
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