Sequencings

Markers / Gene

MCM6

One position in this gene is readable from a home DNA test.

Digesting milk as an adult

rs4988235 · chr2:136,608,646 · G/A · evidence: established

Nearly every mammal switches lactase off after weaning. A single change upstream of the lactase gene keeps it on for life, and it spread through Europe in the last ten thousand years alongside dairying.

If you carryWhat it means
No copiesLikely lactase non-persistent
One copyLikely lactase persistent
Two copiesLikely lactase persistent
Ancestry groupA (the effect version)
African2.7%
American21.6%
East Asian0.0%
European50.8%
South Asian11.3%

1000 Genomes Project phase 3, via Ensembl, retrieved 2026-09-23. These groupings are coarse and flatten a great deal of internal diversity, particularly within Africa. A variant being common somewhere tells you where a piece of your ancestry probably comes from, and nothing else.

Full detail on rs4988235

Where this gene fits

If you have taken a home DNA test, these positions are already in your file.

Read my file