Markers / Gene
near HLA-C
One position in this gene is readable from a home DNA test.
How much HLA-C you display, and HIV control
rs9264942 · chr6:31,274,380 · T/C · evidence: strong
HLA molecules hold up fragments of what is inside your cells for immune inspection. This position controls how much HLA-C is displayed, and people who display more of it control HIV infection considerably better without treatment. It is one of the clearest single-variant effects on any infectious disease.
| If you carry | What it means |
|---|---|
| No copies | You display less HLA-C |
| One copy | You carry one higher-expression copy |
| Two copies | You display more HLA-C |
| Ancestry group | C (the effect version) | |
|---|---|---|
| African | 27.0% | |
| American | 30.4% | |
| East Asian | 39.3% | |
| European | 36.2% | |
| South Asian | 52.5% |
1000 Genomes Project phase 3, via Ensembl, retrieved 2026-09-23. These groupings are coarse and flatten a great deal of internal diversity, particularly within Africa. A variant being common somewhere tells you where a piece of your ancestry probably comes from, and nothing else.
If you have taken a home DNA test, these positions are already in your file.
Read my file