Sequencings

Markers / Gene

SLC30A8

One position in this gene is readable from a home DNA test.

The zinc transporter inside insulin granules

rs13266634 · chr8:118,184,783 · C/T · evidence: established

Insulin is stored in the pancreas packed around zinc, and this transporter loads the zinc in. The variant version is associated with lower risk of type 2 diabetes. Unusually, rare mutations that break the gene completely are protective too, which is why it became a drug target.

If you carryWhat it means
No copiesYou have the higher-risk version on both copies
One copyYou carry one lower-risk copy
Two copiesYou have the lower-risk version on both copies
Ancestry groupT (the effect version)
African7.4%
American26.7%
East Asian45.7%
European28.3%
South Asian25.5%

1000 Genomes Project phase 3, via Ensembl, retrieved 2026-09-23. These groupings are coarse and flatten a great deal of internal diversity, particularly within Africa. A variant being common somewhere tells you where a piece of your ancestry probably comes from, and nothing else.

Full detail on rs13266634

Where this gene fits

If you have taken a home DNA test, these positions are already in your file.

Read my file