rs1805007
Red hair variant R151C
What this position does
MC1R decides which of the two pigments your skin and hair make. Several partly-broken versions push production towards the red-yellow pigment, and this is the strongest of the common ones.
What each result means
| If you carry | What it means |
|---|---|
| No copies of the effect version CC | You do not carry this red-hair variant Neither copy carries this variant. |
| One copy CT | One copy, which usually shows as fair, freckled skin rather than red hair Carriers often have fair skin, freckles and sometimes a red beard without red hair on the head. One copy also raises sun sensitivity. |
| Two copies TT | Two copies, so red hair and very fair skin are highly likely Two copies of a strong red-hair variant. Red hair and very fair, freckled, burn-prone skin are highly likely. |
Worth knowing. MC1R variants raise melanoma risk independently of how much sun you get. Fair, freckled skin deserves the same care whatever the reason for it.
How common each version is
| Ancestry group | T (the effect version) | |
|---|---|---|
| African | 0.3% | |
| American | 1.6% | |
| East Asian | 0.1% | |
| European | 7.2% | |
| South Asian | 0.5% |
1000 Genomes Project phase 3, via Ensembl, retrieved 2026-09-23. These groupings are coarse and flatten a great deal of internal diversity, particularly within Africa. A variant being common somewhere tells you where a piece of your ancestry probably comes from, and nothing else.
How many people carry each result
| Ancestry group | CC | CT | TT |
|---|---|---|---|
| African | 657 / 661 | 4 / 661 | 0 / 661 |
| European | 435 / 503 | 64 / 503 | 4 / 503 |
| East Asian | 503 / 504 | 1 / 504 | 0 / 504 |
| South Asian | 484 / 489 | 5 / 489 | 0 / 489 |
| American | 336 / 347 | 11 / 347 | 0 / 347 |
Counts of people, not modelled frequencies: every one of the 2,504 individuals sequenced by the 1000 Genomes Project phase 3, tallied by the genotype they carry. Deriving these from allele frequencies instead would assume random mating inside each group and undercount the homozygotes.
How to find out which you have
If you have taken a test with 23andMe, AncestryDNA, MyHeritage, Family Tree DNA, TellMeGen or Living DNA, this position is very likely already in the raw data file they gave you. You do not need another test.
One thing to watch if you look it up by hand: testing companies report some positions from one DNA strand and some from the other, and the file does not say which. Read the letters as they appear and you will get the opposite of the truth for some positions. Sequencings resolves that automatically.
Source
Coordinates and allele pair verified against Ensembl GRCh37. Direction of effect verified against VEP protein consequences or 1000 Genomes population frequency. Category: Trait.
Related
- rs1805008 — Red hair variant R160W
Where this fits
Common questions
What is rs1805007?
rs1805007 is a position in the MC1R gene on chromosome 16. MC1R decides which of the two pigments your skin and hair make. Several partly-broken versions push production towards the red-yellow pigment, and this is the strongest of the common ones.
What does it mean if I have TT at rs1805007?
Two copies, so red hair and very fair skin are highly likely. Two copies of a strong red-hair variant. Red hair and very fair, freckled, burn-prone skin are highly likely.
What does it mean if I have CC at rs1805007?
You do not carry this red-hair variant. Neither copy carries this variant.
How do I find out my rs1805007 genotype?
If you have taken a home DNA test, this position is very likely in the raw data file you were given. Sequencings reads that file in your browser without uploading it, and resolves which DNA strand each position was reported from, which is the step most manual lookups get wrong.
This is reference information, not medical advice, and not a diagnosis. See the medical disclaimer. Category: Trait.