Markers / Gene
ABCG2
One position in this gene is readable from a home DNA test.
ABCG2, statin response and uric acid
rs2231142 · chr4:89,052,323 · G/T · evidence: established
ABCG2 is a transporter that pumps drugs and waste out of cells. This reduced-function change raises blood levels of rosuvastatin and is also one of the strongest common genetic causes of raised uric acid and gout.
| If you carry | What it means |
|---|---|
| No copies | You have normal transporter function |
| One copy | Decreased function |
| Two copies | Poor function |
| Ancestry group | T (the effect version) | |
|---|---|---|
| African | 1.3% | |
| American | 14.1% | |
| East Asian | 29.1% | |
| European | 9.4% | |
| South Asian | 9.7% |
1000 Genomes Project phase 3, via Ensembl, retrieved 2026-09-23. These groupings are coarse and flatten a great deal of internal diversity, particularly within Africa. A variant being common somewhere tells you where a piece of your ancestry probably comes from, and nothing else.
Where this gene fits
If you have taken a home DNA test, these positions are already in your file.
Read my file