rs10246939
Bitter receptor, second position
What this position does
The second of the three positions that define the two common versions of the TAS2R38 bitter receptor.
What each result means
| If you carry | What it means |
|---|---|
| No copies of the effect version TT | Non-taster version at this position Two copies of the version carried by the poorly-working receptor. |
| One copy CT | One of each Heterozygous at this position. |
| Two copies CC | Taster version at this position Two copies of the version carried by the working receptor. |
How common each version is
How many people carry each result
How to find out which you have
If you have taken a test with 23andMe, AncestryDNA, MyHeritage, Family Tree DNA, TellMeGen or Living DNA, this position is very likely already in the raw data file they gave you. You do not need another test.
One thing to watch if you look it up by hand: testing companies report some positions from one DNA strand and some from the other, and the file does not say which. Read the letters as they appear and you will get the opposite of the truth for some positions. Sequencings resolves that automatically.
Source
Coordinates and allele pair verified against Ensembl GRCh37. Direction of effect verified against VEP protein consequences or 1000 Genomes population frequency. Category: Trait.
Related
- rs1726866 — Tasting bitterness in brassicas
Where this fits
Common questions
What is rs10246939?
rs10246939 is a position in the TAS2R38 gene on chromosome 7. The second of the three positions that define the two common versions of the TAS2R38 bitter receptor.
What does it mean if I have CC at rs10246939?
Taster version at this position. Two copies of the version carried by the working receptor.
What does it mean if I have TT at rs10246939?
Non-taster version at this position. Two copies of the version carried by the poorly-working receptor.
How do I find out my rs10246939 genotype?
If you have taken a home DNA test, this position is very likely in the raw data file you were given. Sequencings reads that file in your browser without uploading it, and resolves which DNA strand each position was reported from, which is the step most manual lookups get wrong.
This is reference information, not medical advice, and not a diagnosis. See the medical disclaimer. Category: Trait.